New Drug Could Extend the Lifespans of Giant Dog Breeds::The drug, LOY-001, could be available to the public as soon as 2026.

  • AutoTL;DR@lemmings.worldB
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    1 year ago

    This is the best summary I could come up with:


    The animal pharmaceutical company Loyal announced that the FDA has accepted the development of a drug that could extend the lifespans of large and giant dog breeds.

    In a blog post published today, Celia Halioua, the founder and CEO of Loyal, said that the company earned the FDA’s acceptance of the drug.

    “In regulatory parlance,” Halioua wrote, “we have completed the technical effectiveness portion of our conditional approval application for LOY-001’s use in large dog lifespan extension.”

    Giant dogs are the ones that might make you gawk on the street: Great Danes, Irish wolfhounds, and Anatolian shepherds to name a few.

    “At Loyal, we see the short lifespan of big dogs not as inevitable, but as a genetically-associated disease caused by historical artificial selection, and therefore amenable to targeting and treatment with a drug.”

    According to Halioua’s post, breeding large dogs for their size caused elevated levels of IGF-1, a hormone that promotes cell growth.


    The original article contains 431 words, the summary contains 155 words. Saved 64%. I’m a bot and I’m open source!

    • ColorcodedResistor@lemm.ee
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      1 year ago

      People: thanks to those punnet squares, we have been able to disable pug breeds and give larger breeds severe life altering conditions.

      Big Pharma: “At Loyal, we see the short lifespan of big dogs not as inevitable, but as a genetically-associated disease caused by historical artificial selection, and therefore amenable to targeting and treatment with a drug.”

      People: phew, thank god we don’t have to endure any consequences for manipulating the genetics of dogs back and forth like a game of tennis.